As with non-small cell cancer, a new or changing cough, particularly if phlegm contains blood, is a common symptom, along with hoarseness and shortness of breath or increased shortness of breath on exertion. There may also be an increase in the amount of sputum , recurrent episodes of lung infection (sometimes in the same lobe of the lung as the cancer), weight loss and swelling of the face or arms.
If the tumor has metastasized, the symptoms can include severe headaches, double vision, and pain in the bones, chest, abdomen, neck and in the arms.
One point that needs to be emphasized is that this disease is commonly widespread at the time of diagnosis.